Marco Marra, M.Sc.

Marco Marra M.Sc. | Ph.D. student for the ERC project BioMechTools | Orthopaedic Research Laboratory Nijmegen, radboudumc, Radboud University Nijmegen Medical Centre. Marco.MarraAapjeradboudumc.nl
T: +31 (0) 24 36 17379
About Me
Research Impression
Publications

About Me

Having always been attracted by science and technical matters, I decided to pursue the scientific education. I chose Turin as destination for my biomedical engineering studies. In 2011 I got my bachelor degree from Polytechnic University of Turin with an original project of a telemedicine service for prisoners. During the master I spent one year at the Royal Institute of Technology of Stockholm, studying and working on my master degree project in trauma biomechanics, which resulted in my master thesis “Study of dens fracture in the elderly, and the influence of osteoporosis with a finite element model”. After graduation in Biomedical Engineering in 2013, I decided to further enhance my knowledge in biomechanics and modelling by pursuing the doctoral studies at ORL, Nijmegen, The Netherlands.

As of October 2013, I’m a Ph.D. student in the project ‘BioMechTools’ under the supervision of Prof. Dr. Ir. Nico Verdonschot. My tasks focus at developing and testing an integrated modelling approach which includes both finite element and musculoskeletal patient-specific models of the active structures in the lower extremity.
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Research Impression

One of the factors which would facilitate the introduction of musculoskeletal models into clinical practice is the fast and easy generation of personalized models. Although such methods have already been developed (see www.tlemsafe.eu ), they still fail at representing pathological cases.

The goal of my research is to develop and validate methods for the generation of an integrated patient-specific finite-element model of the lower extremity, that is able to simulate a direct interaction between muscle activation, deformation and kinematics, and can be used as a diagnostic tool for pathologies within the musculoskeletal system of the lower limb. Many challenges are present in such a task: the automated registration techniques need to be improved for representing pathological cases as well as the other relevant soft tissue aspects; muscles multi-dimensional deformation has to be captured and implemented in our integrated model. Finally, muscle contraction, dynamics and optimization strategies, tissues interaction and soft tissue deformations are all factors that increase the numerical complexity of the problem, that needs to be kept to a minimum.
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Publications

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Our project on patient-specific musculoskeletal modelling of TKA has been awarded the first prize in the Grand Knee Challenge competition during the 7th World Congress of Biomechanics, July 6-11, 2014, Boston, Massachusetts USA.
Presentation Abstract:
Patient-specific Musculoskeletal Modelling of Total Knee Arthroplasty using Force-dependent Kinematics
Author(s):
M. S. Andersen 1, M. A. Marra 2, V. Vanheule 3, R. Fluit 4, N. Verdonschot 2, J. Rasmussen 1;
1) Aalborg University, Aalborg East, DENMARK; 2) Radboud University Nijmegen Medical Centre, Nijmegen, NETHERLANDS; 3) Materialise N.V., Leuven, BELGIUM; 4) University of Twente, Enschede, NETHERLANDS;
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